A passenger train partially derailed in eastern Iran early Wednesday, killing at least 10 passengers and injuring 50 more, some critically, state TV said.
The report said the number of casualties could rise, though initial details about the disaster remained unclear.
Four of the seven cars in the train derailed in the early morning darkness near the desert city of Tabas, the report said.
Rescue teams on ambulances and three helicopters were arriving in the remote area where communication is poor.
The derailment happened some 50 kilometers (30 miles) to Tabas, about 550 kilometers (340 miles) southeast of the capital, Tehran, on the rail that links the town to the central city of Yazd.