Flight operations of Vistara were impacted at Delhi and Mumbai airports, mainly due to the non-availability of pilots, according to industry sources.
Some flights were cancelled and many were delayed at the two airports on Wednesday, they said.
Specific details could not be immediately ascertained and there was no comment from Vistara.
The full-service carrier operates more than 300 flights daily with a fleet of 67 planes.
The sources said some pilots reported sick which impacted the schedule. Also, there are concerns among pilots about the new salary structure being implemented at the airline, which will be similar to that of Air India.